So Medford not only gave us gypsy moths, it gave us 'Jingle Bells'

The "Thanksgiving Song" (Over The River And Throught The Woods" was also written in Medford. The woman who wrote it lived on Salem St. (a hotbed of holiday songs apparently). The river referred to is the Mystic. Grandmother's house still stands. It is the big white house with columns on South St. overlooking the river. I believe it is now owned by Tufts and some administrator lives in it.

Back in 2001, the Boston Herald ran an article about this. As they said, it's not really a Christmas song; it's about young men "having a flashy vehicle, driving it too fast and using it to pick up girls." (Sorry, I don't have a link.) And getting in an accident, to boot.

The same street was also the start of the trip "over the [Mystic] river and through the wood, to grandmother's house we go" by Lydia Maria Child -- except she wrote it as grandfather's house.

let's not forget grandfathers house:
http://en.wikipedia.org/wiki/Grandfather's_House