Boston Police report two women were stabbed at 26 Taft St. in Dorchester shortly before 12:25 p.m.
One woman was declared dead at the scene; the second was taken to the hospital, where she died.
Two children were removed from the scene and taken to a local hospital for observation.
A dog was injured in the attack.
Marcus Chavis, 34, of Dorchester, was arrested and charged with two counts of murder and one count of animal cruelty, police say.
Taft Street is where former Mayor Marty Walsh grew up.